England vs Wales LIVE: Six Nations rugby score and latest updates as Alex Dombrandt try puts hosts 17 clear

LIVE – Updated at 18:05

Follow live coverage as England host Wales in a crunch Six Nations match at Twickenham on Saturday evening.

Defeat to Scotland in the opener at Murrayfield leaves little margin for error for today’s hosts and coach Eddie Jones knows nothing less than a win will do with tournament favourites Ireland and France still to come. They will have to do it without Manu Tuilagi, however, with the Sale centre recalled only to later be ruled out by injury. Back row Courtney Lawes is back though and will captain the side while Ben Youngs must surpass Jason Leonard’s record as England’s most capped player as a replacement with Harry Randall continuing as starting scrum-half.

For Wales, Louis Rees-Zammit is the surprise omission with fit-again Josh Adams and Alex Cuthbert preferred on the wings. Number eight Taulupe Faletau will makes his first international appearance for 11 months, having successfully proved his fitness following a long-term ankle injury.

Follow all the latest updates and analysis:

Basham had his arm out, he would have ran in but the ball can’t be recycled to him. More heartbreak for Wales as England turn it over and kick away.

That is a relief for England as Wales looked dangerous, if Basham got the ball he would have been in.

A huge hit from Itoje as Wales again look to attack but Dombrandt has won a turn over. At the moment everything is going against Wales with Slade clearing the lines.

But this time England’s line-out goes awry and they win a penalty to boot it away. Back and forth with England absorbing pressure.

T Williams looks to strike back with a great break and Wales now putting it through the hands. The hosts manage to get the ball back with a knock on from Wales to see the ball