Chiefs-49ers 'will probably be most highly-wagered NFL game' so far in 2024

Whenever the Kansas City Chiefs and San Francisco 49ers meet on the football field these days, Las Vegas sportsbooks see dollar signs.

That’s because it’s easy for customers to get to the window either way. 

In one corner, you have the three-time Super Bowl winning trifecta of Patrick Mahomes, Travis Kelce and Andy Reid. An NFC juggernaut with one of the league’s most-talented rosters stands in the other corner.

The storylines and betting angles flow from every direction, and that will be the case as the two face off this weekend on FOX and the FOX Sports app.

"This will probably be our most highly-wagered NFL game up to this point in the season," Westgate SuperBook vice president of risk management Jeff Sherman told FOX Sports. "It’ll see the most volume ‘til now, and we expect split opinions and solid two-way action on both sides.

"We’re sitting Niners -1.5 right now. We opened -1 and wrote early Niners’ support from people betting the Super Bowl revenge angle. We’ve seen more parlays on the Niners at this point, too, and I expect the number to rise a little bit. Then we’ll eventually write Chiefs moneyline action to even it out.

"We should be a little heavier on the Niners side, but it feels like 1.5 is the sweet spot for this game. I don’t see it getting towards San Francisco -2.5/3 or PK/Kansas City -1 on the other end. It’s a good number where it’s at."

The appetite to bet both teams will likely make for a happy bottom line in the game. For every dollar that believes in San Francisco avenging its Super Bowl loss from February, there’s a dollar eyeing Mahomes as an underdog.

And maybe you’ve heard Reid is 21-4 all-time off a bye.

"News to me," Sherman cracked sarcastically.

Mahomes enters Sunday’s tilt with six