Best ManningCast moments from San Francisco 49ers vs. LA Rams

The San Francisco 49ers beat the Los Angeles Rams 24-9 on Monday Night Football in the final game of Week 4, and Peyton and Eli were on the ManningCast to break down the action.

These two teams last met in January's NFC title game, where the 49ers fell 20-17 to the eventual Super Bowl champs. Despite that victory, the team has struggled in recent years against San Francisco. The Rams have recorded seven consecutive regular-season losses against the 49ers — and five of those have been decided by one score.

Peyton and Eli welcomed Philadelphia Eagles QB Jalen Hurts, Golden State Warriors star Stephen Curry and Emmy Award-winning actor Jon Hamm for this NFC West showdown.

Here are some of the best ManningCast moments from Week 4:

Hamm has now been a guest on both shows.

A full circle moment <a href=«https://twitter.com/nbcsnl?ref_src=» https:>@nbcsnl

pic.twitter.com/zRXghD3zjH

Peyton broke down Bobby Wagner's tackle on a fan who ran on the field.

Read more: Rams' Wagner flattens fan who evades security

Peyton & <a href=«https://twitter.com/EliManning?ref_src=» https:>@EliManning

will do play-by-play of anything… including a streaker on the field