49ers' Christian McCaffrey's Week 1 status in question after injury

Fox News Flash top sports headlines are here. Check out what's clicking on Foxnews.com.

The San Francisco 49ers' quest to get over the Super Bowl hump hit a bump Tuesday.

Head coach Kyle Shanahan announced that reigning Offensive Player of the Year Christian McCaffrey will miss a "couple weeks" because of a calf injury.

McCaffrey played in 10 total games from 2020 to 2021 due to injuries.

CLICK HERE FOR MORE SPORTS COVERAGE ON FOXNEWS.COM

Christian McCaffrey of the San Francisco 49ers carries the ball against the Arizona Cardinals at State Farm Stadium Dec. 17, 2023, in Glendale, Ariz. (Cooper Neill/Getty Images)

The 49ers' season doesn't start for another five weeks. So, that gives McCaffrey plenty of time to return. But Shanahan did note that McCaffrey will not participate in the preseason.

It has become increasingly rare to see star veterans get action in the preseason. So, who knows whether McCaffrey would have even seen a snap anyway. He's played in just two preseason games since 2019.

It also should be noted that McCaffrey is on the cover of Madden 25, and fans are nervous that this is the rebirth of the so-called Madden Curse.

Christian McCaffrey of the San Francisco 49ers before a game against the Seattle Seahawks at Lumen Field Nov. 23, 2023, in Seattle.  (Steph Chambers/Getty Images)

JIM HARBAUGH DENIES COMMITTING VIOLATIONS AFTER NCAA'S REPORTED NOTICE OF ALLEGATIONS: 'I DO NOT APOLOGIZE'

Earlier in the 21st century, cover athletes for the game often had tumultuous seasons immediately after. Dante Culpepper (2001), Donovan McNabb (2006), Shaun Alexander (2007) and Vince Young (2008) are some of the most notable examples.

However, there hasn't been a "curse" since Rob Gronkowski graced the cover in 2016 and