2026-27 NFL Odds: Which Quarterbacks Will Start Week 1?

The hopes of NFL franchises — and their fanbases — often reside with their starting quarterbacks.

Let's check out the odds for which signal-callers will start for six franchises, at DraftKings Sportsbook as of April 30.

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Cardinals Week 1 starting quarterback

Jacoby Brissett: -330 (bet $10 to win $13.03 total)
Gardner Minshew: +420 (bet $10 to win $52 total)
Carson Beck: +750 (bet $10 to win $85 total)

What to know: The Cardinals released seven-year starter Kyler Murray back in March, and he signed a one-year deal with the Vikings. With Murray battling injury much of last season, Brissett served as the Cardinals' starter for 12 games, going 1-11 in those starts. Minshew will be on his fifth team in five years, and is 2-8 as a starter over the last two seasons. As for Beck, he was selected by Arizona in the third round of the 2026 NFL Draft.

Falcons Week 1 starting quarterback

Tua Tagovailoa: -125 (bet $10 to win $18 total)
Michael Penix Jr.: -102 (bet $10 to win $19.80 total)

What to know: This one is up in the air. Tagovailoa started 76 games over the past six seasons in Miami, going 44-32. In five of those years, the Dolphins had a winning record when Tagovailoa started, but Miami only made the playoffs once, losing in the wild-card round. He was released by Miami in March and signed a one-year deal with Atlanta. As for Penix, he's started 12 games across two seasons with the Falcons, going 4-8, including 3-6 as the starter last season.

Browns Week 1 starting quarterback

Deshaun Watson: -135 (bet $10 to win $17.41 total)
Shedeur