2025 NFL Week 3 betting - Monday Night Football: Detroit Lions-Baltimore Ravens odds, picks - ESPN

Week 3 of the NFL season wraps up with the Baltimore Ravens playing host to the Detroit Lions on «Monday Night Football.»

The Ravens trounced the Browns in Week 2 to move to 1-1, and the Lions blew out the Bears to even their record.

Baltimore is a 4.5-point favorite for Monday's game, with the total sitting at 53.5, the highest of the week.

From odds and trends to picks, props and analysis from our experts, here's everything you need to help make your decisions at the betting window.

Note: Odds at time of publication. For the latest updates, visit ESPN BET.

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Detroit Lions at Baltimore Ravens

Ravens -4.5 (Even)

Maldonado: Detroit made a statement with a 52-point outburst in Week 2, but this road trip to Baltimore is different. The Ravens lead the NFL in explosive play rate, with over a quarter of their snaps going for 10-plus yards. Keep pace. The bigger mismatch is that Lamar Jackson has been elite when not being pressured, and Detroit ranks 26th in pressure rate. Add Derrick Henry facing a defense allowing 4.7 YPC, and Baltimore has the edge.

Over

Under

Over

Dan Orlovsky and Adam Schefter debate which offense will dominate as Lamar Jackson and the Ravens meet the Lions head-to-head Monday night.

Lamar Jackson 2+ passing TDs and Derrick Henry anytime TD (+129)

Maldonado: I love this combo. The Lions blitz a ton but are bottom five in pressure rate, which is basically begging Jackson to carve them up when he's clean. He's sitting at 9.5 yards per attempt with an 18% touchdown rate in those spots (the league average is around 4-5%). It's a small early-season sample, but it highlights just how dangerous Jackson has been when teams don't get home with pressure. Add