2024 NFL Week 4 betting - Cowboys-Giants odds, picks, lines - ESPN

Week 4 of the NFL season kicks off with a matchup of NFC East rivals when the Dallas Cowboys visit the New York Giants on «Thursday Night Football» (8:15 p.m. ET).

The Cowboys (1-2) have lost two straight home games after defeating the Cleveland Browns on the road to open their season. The Giants (1-2), meanwhile, are coming off their first win, also on the road against the Browns.

Dallas has dominated the matchup between the two teams of late, winning six straight in the series and 13 of 14. The spread on Thursday's game opened at Cowboys -4 and has continued to tick up.

Giants rookie wide receiver Malik Nabers, the sixth overall pick in April's draft, is coming off two straight stellar performances and has risen to No. 2 in the Offensive Rookie of the Year odds (+260), trailing only Washington Commanders quarterback Jayden Daniels (+150). Nabers is second in the league with 23 receptions and has hauled in three receiving scores (T-1).

The Cowboys (-105 to make the playoffs) have dipped to 20-1 to win the Super Bowl, while the Giants (12-1 to make the playoffs) remain long shots at 300-1.

Odds current as of publish time, courtesy of ESPN BET

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Spread: Cowboys -6
Money line: Cowboys (-250), Giants (+210)
Over/Under: 45.5

First-half spread: Cowboys -3.5 (Even), Giants +3.5 (-120)
Cowboys total points: 25.5 (Over -120/Under -110)
Giants total points: 19.5 (Over -120/Under -110)

Dak Prescott total passing yards: 249.5 (Over -135/Under +105)
Prescott total passing TDs: 1.5 (Over -140/Under +110)
Daniel Jones total passing yards: 199.5