2024 NFL Week 1 betting - Jets-49ers odds, picks, lines - ESPN

Week 1 NFL action wraps up Monday night with Aaron Rodgers and the New York Jets visiting the defending NFC champion San Francisco 49ers. Rodgers, who suffered a torn Achilles only four snaps into last season, won't be playing far from his college stomping grounds at Cal, but his Jets come in as 4.5-point underdogs.

New York finished 7-10 last season but, buoyed by Rodgers' return, is the favorite to win the AFC East (+160). Meanwhile, the 49ers are coming off a Super Bowl berth and are 6-1 to hoist the Lombardi Trophy this season, trailing only the Kansas City Chiefs (5-1).

Monday Night Football kicks off at 8:20 p.m. ET (on ESPN ABC ESPN+).

Odds current as of publish time, courtesy of ESPN BET

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Spread: 49ers -4.5
Money line: Jets (+175), 49ers (-210)
Over/Under: 43.5

First-half spread: 49ers -2.5 (-140), Jets +2.5 (+113)
Jets total points: 19.5 (Over -120/Under -110)
49ers total points: 24.5 (Over +105/Under -135)

Brock Purdy total passing yards: 249.5 (Over +105/Under -140)
Purdy total passing TDs: 1.5 (Over TBD/Under TBD)
Aaron Rodgers total passing yards: 249.5 (Over +115/Under -155)
Rodgers total passing TDs: 1.5 (Over +115/Under -145)

Christian McCaffrey total rushing yards: 79.5 (Over +105/Under -140)
Breece Hall total rushing yards: 69.5 (Over +105/Under — 140)

Garrett Wilson total receiving yards: 69.5 (Over -120/Under -110)
Brandon Aiyuk total receiving yards: 59.5 (Over +105/Under -135)
Deebo Samuel Sr. total receiving yards: 49.5 (Over -110/Under -115)
George Kittle total receiving yards: 44.5 (Over -100/Under -130)
McCaffrey total receiving