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Pau head coach Sebastien Piqueronies was banned for 10 weeks on Thursday after European Professional Club Rugby (EPCR) found him guilty of misconduct for an angry confrontation with the referee after a narrow loss to the Cheetahs.
The Cheetahs will be without the services Springbok Oupa Mohoje after the flanker received a three-week suspension following foul play in their Challenge Cup win over Pau.
Springbok Willem Alberts is back at lock for the Lions as they take on Stade Francais Paris on Friday in their Challenge Cup encounter at Ellis Park.
Connacht will be without Josh Murphy and Dylan Tierney-Martin for Friday's Challenge Cup trip to Brive.
Wing Edwill van der Merwe scored twice as the Lions and Dragons played to a thrilling 31-31 draw in a familiar-looking Challenge Cup contest at Ellis Park on Saturday.
The Connacht players would have been forgiven for putting their feet up following their double-scores victory over Benetton last weekend, but Peter Dooley and his fellow forwards were quickly back to work.
The Lions and Cheetahs teams for their Challenge Cup debuts were named on Friday.