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John Ryan will make his 200th appearance for Munster when they visit Edinburgh in the BKT United Rugby Championshipon Friday while Simon Zebo is handed his first league start since September.
Bernard Jackman believes Antoine Frisch could make a bigger impact at Munster than international centres Malakai Fekitoa and Damian de Allende.
Munster have named a youthful looking squad for Thursday's historic match against a South Africa XV at Páirc Úi Chaoimh.
Munster will not train at Páirc Uí Chaoimh ahead of their game against South Africa because Graham Rowntree wants it to be a "special moment" for his players when they run onto the pitch for the first time.
John Ryan and Mike Haley come into the Munster starting line-up for Saturday's interprovincial derby against Ulster, live on RTÉ2 and RTÉ Player, with Simon Zebo named on the bench.
Joey Carbery will make his first out-half start of the season in tomorrow night's BKT United Rugby Championship meeting with the Bulls at Thomond Park.
Connacht and Munster have both been able to welcome back key players for Friday's crucial BKT United Rugby Championship interprovincial match at the Sportsground.
Damian de Allende was always going to be a tough act to follow.