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The Dragons will be aiming to complete the double while the Scarlets will be after revenge when the two regions lock horns once again at Rodney Parade this afternoon (3pm). It was the Men of Gwent who recorded a surprise 38-27 victory down in Llanelli last weekend, just their second win of the season in all competitions.
The Scarlets are looking to continue their tilt at the United Rugby Championship this evening when they welcome the Dragons to Llanelli.
The Dragons welcome Gloucester to Rodney Parade for their final Challenge Cup pool stage match.
The Dragons are desperately looking to give their fans something to cheer about but they will once again be up against it when they take on the Sharks.
Check out the team news and our predictions for the matches below.
Round 15 of the United Rugby Championship season kicks off with two games on Friday as the Sharks host the Dragons before Glasgow Warriors face Zebre Parma.
The Dragons face a daunting challenge this evening as they head to Loftus Versfeld to face the Bulls.
Blue Bulls coach Jake White has made three changes to his run-on team for their engagement against the Dragons at Loftus on Saturday.