49ers RBs Christian McCaffrey, Jordan Mason both headed to IR - ESPN
The San Francisco 49ers will be without their top two running backs for the foreseeable future.
Kyle Shanahan Sport News
49ers' Christian McCaffrey suffered 'potentially' season-ending knee injury vs Bills, coach says
The Buffalo Bills beat the San Francisco 49ers 35-10 in a game that was dominated by Josh Allen. Craig Carton, Danny Parkins, Mark Schlereth, and Greg Jennings ask if the Bills are the best team in the AFC.
49ers RB Christian McCaffrey injures PCL in loss to Bills - ESPN
ORCHARD PARK, N.Y. — San Francisco 49ers running back Christian McCaffrey suffered what is believed to be an injury to the posterior cruciate ligament in his right knee Sunday night, leaving the rest of his season in jeopardy, according to coach Kyle Shanahan.
49ers' Purdy, Ward expected to play; Williams, Bosa ruled out - ESPN
SANTA CLARA, Calif. — Barring unforeseen circumstances between now and Sunday night's game, San Francisco 49ers quarterback Brock Purdy will return against the Buffalo Bills.
49ers 'embarrassed' in 28-point loss, their worst against Packers - ESPN
GREEN BAY, Wis. — Moments after suffering the franchise's worst loss to the Green Bay Packers in the history of the series — and the third-largest defeat of any kind since he became head coach in 2017 — the San Francisco 49ers' Kyle Shanahan was asked to name the most disappointing part of his team's performance.
49ers rule out QB Brock Purdy, DE Nick Bosa for Packers game - ESPN
SANTA CLARA, Calif. — Entering an important matchup with the Green Bay Packers on Sunday, the San Francisco 49ers will be without starting quarterback Brock Purdy and defensive end Nick Bosa.
49ers hope Nick Bosa's injury isn't long term during critical stretch
The San Francisco 49ers got a taste of what their defense looks like without Nick Bosa in the second half of a loss to the Seattle Seahawks.
49ers QB Brock Purdy dealing with right shoulder soreness - ESPN
SANTA CLARA, Calif. — On an already lengthy injury list full of some of the biggest names on the team, the San Francisco 49ers had another significant addition Monday: quarterback Brock Purdy.