For possibly the first time since August, Manchester United's back-four should pick itself when Manchester City visit Old Trafford on Sunday afternoon.
The Reds' defensive department has been hampered by injury and illness-related issues since the opening month of the season, meaning it has been impossible for manager Erik ten Hag to find a settled and consistent rearguard.
Three of the four members that started the opening two games of the season are expected to miss Sunday's derby, highlighting the sheer size of the problem.
Aaron Wan-Bissaka, Lisandro Martinez and Luke Shaw joined Raphael Varane in forming the back-four for United's opening two Premier League outings this season, starting the win over Wolves and defeat by Tottenham Hotspur, but only the latter is currently fit.