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Arsenal face a stiff test of their Premier League title credentials when they travel to Chelsea on Sunday, while Liverpool desperately need to win at Tottenham to claw back ground on the top four.
Ireland centre Robbie Henshaw has been ruled out of Saturday's autumn international against South Africa and will be replaced by Stuart McCloskey.
LONDON : Argentina will field two new front rowers and have made a switch on the wing in three changes for Sunday’s test against England at Twickenham.
Former Australia playmaker Matt Giteau believes the Wallabies are in for a difficult time on Saturday against a "super-confident" France, hosts of the 2023 World Cup.
DUBLIN : Ireland host South Africa in Dublin on Saturday in an autumn international clash between the top side in the global rankings and the world champions, which comes 10 months before they meet again at the Rugby World Cup in France.
Toulouse duo Romain Ntamack and Cyril Baille will start France's opening autumn international against Australia in Paris on Saturday despite recent injury troubles that have restricted their playing time at club level.
CARDIFF : New Zealand made extensive changes to their lineup as they reverted to a strong selection for Saturday’s test against Wales after fielding an experimental team last week in Japan.
Napoli have swept to a five-point lead in Serie A on the back of an unbeaten 12-match run but that streak will be put to the test on Saturday when they travel to second-placed Atalanta.