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Elliot Daley, Dan Cole, Max Malins and Ben Curry were included in England coach Steve Borthwick's Six Nations squad on Monday having been dropped by Eddie Jones but there was no place for wingers Jonny May and Jack Nowell or number eight Billy Vunipola.
Leinster have confirmed that Johnny Sexton and Tadhg Furlong are both expected to be available for the start of Ireland's Guinness Six Nations campaign.
Owen Farrell could miss England's Six Nations opener against Scotland next month if he is cited for a dangerous tackle during Saracens' 19-16 Premiership win over Gloucester on Saturday.
England have appointed Nick Evans as their attack coach as new boss Steve Borthwick finalises his management team for the upcoming Six Nations.
Wales wing Louis Rees-Zammit has emerged as an injury doubt for Wales ahead of their Six Nations opener against Ireland on 4 February.
Wales boss Warren Gatland has received a major boost ahead of this season's Six Nations Championship - where they'll face Ireland in Cardiff in their opener on 4 February - with Liam Williams returning to action.
Springbok fulcrum lock Eben Etzebeth, a proponent of aligning the global rugby schedule, said he’d be for the idea of South Africa joining Europe’s Six Nations tournament.
Eddie Jones has been sacked as England head coach after presiding over their worst year since 2008.