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Ireland will claim a second straight title if they defeat England later on Saturday thanks to the Italians winning a breathless match in which Juan Ignacio Brex, debutant Louis Lynagh and Stephen Varney all scored tries.
Ireland saw their Grand Slam dream denied in Twickenham as England's Marcus Smith scored a drop goal in the last play of the game to claim a thrilling Guinness Six Nations win.
Italy wing Louis Lynagh joked that he may retire from international rugby after a dream debut in which he scored a try to help his side to a famous 31-29 victory over Scotland on Saturday, their first home win in the Six Nations since 2013.
Scotland's Guinness Six Nations campaign unravelled in disastrous fashion in Rome as they crashed to a first defeat against Italy since 2015.
Ireland will open their 2025 Guinness Six Nations campaign with a home fixture at the Aviva Stadium against England.
In rugby terms, Calvin Nash is a bit of a unicorn; both a prodigious talent and a late developer.
It's difficult to make a compelling argument that England can beat Ireland today.
Fabien Galthie readily accepts that France "are not at the level we want to be" during what has proved to be a spluttering Guinness Six Nations campaign.