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The 22-year-old Juventus forward has not played because of a groin injury since the 4-3 defeat to Benfica which knocked the Italians out of the Champions League at the end of last month, prompting speculation that he might be left out of the squd.
The 20-year-old Barcelona forward was not used in September's Nations League clashes and has not been at his best for his club this season.
Mane's involvement in the tournament was in doubt after he limped off during his club Bayern Munich's 6-1 win over Werder Bremen on Tuesday.
The United States are playing in the finals for the first time in eight years.
The Manchester United striker, 37, has not been first choice for his club this season but will be part of his country's bid to win the tournament for the first time in their history.
Morocco coach Walid Regragui called up Chelsea forward Hakim Ziyech and Paris Saint-Germain's Achraf Hakimi for his World Cup squad Thursday, less than two weeks before they kick off against Croatia.
Borussia Dortmund captain Marco Reus bas been omitted by head coach Hansi Flick from Germany's squad for the World Cup, while 2014 World Cup hero Mario Goetze makes a shock return after a five-year absence.
Manchester City goalkeeper Zack Steffen was the surprise omission as United States coach Gregg Berhalter revealed his 26-man squad for the World Cup on Wednesday.