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Matt Doherty's season-ending knee injury meant Antonio Conte had to make a change to his Tottenham team that won at Aston Villa last time out. Sergio Reguilon, who replaced the Republic of Ireland international early on at Villa Park, was the man to come into the side as Ryan Sessegnon remained on the bench.
Team news, stats, predictions and how to follow the Premier League this weekend, including Leicester vs Newcastle, live on Sky Sports. Premier League fixtures | Premier League tableWatch PL highlights and clips for free on Sky SportsTottenham vs Brighton - Saturday, 12.30pm
Tottenham can up the pressure on their top-four rivals this weekend by securing victory against Brighton & Hove Albion in the early kick-off. Now three points ahead of Arsenal after Antonio Conte's side capitalised on their defeat last Saturday, Spurs can extend their lead to six points before the Gunners take on Southampton.
Ryan Sessegnon's Tottenham career has been extremely stop-start to say the least but he is now starting to make a real impact in north London. Starting in six successive games for Spurs at left wing-back and appearing to have nudged ahead of Sergio Reguilon in the pecking order, the 21-year-old was dealt a cruel blow at the start of March after sustaining a hamstring injury.
Tottenham could use midfielder Giovani Lo Celso in a swap deal to bring in Villarreal defender Pau Torres in the summer, according to reports.
Ryan Sessegnon has admitted that Antonio Conte did not say anything to him in the aftermath of his red card in Tottenham's embarrassing 2-1 Europa Conference League defeat against NS Mura. Missing a lot of football in the opening few months of the season through injury, the 21-year-old was handed a huge opportunity to impress in only the head coach's fourth game in charge of Spurs.
Fulham are a traditional club steeped in history and they have had a habit of bringing some talented youngsters through at Craven Cottage.
Tottenham have been handed a double injury boost ahead of their trip to Aston Villa with Sergio Reguilon and Ryan Sessegnon both available again after injury.