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Ireland forwards Caelan Doris and Rónan Kelleher are injury doubts ahead of Saturday's Six Nations clash with Wales, while Iain Henderson and Cormac Izuchukwu are definitely out.
The fine margins that can swing international rugby were well summed up by the final moments of Ireland's first half against Scotland on Sunday.
Ireland's bid to retain their Guinness Six Nations title remains firmly on course after a 32-18 win over Scotland at Murrayfield.
Caelan Doris believes his side will have their hands full in containing Scotland's co-captain Rory Darge around the breakdown, when the sides meet in the Guinness Six Nations this afternoon.
Ireland wing Mack Hansen will miss Sunday's Six Nations match against Scotland due to a hamstring issue and will be replaced by Calvin Nash, the Irish Rugby Football Union (IRFU) said.
Peter O'Mahony and Robbie Henshaw return to the Ireland side for their Guinness Six Nations encounter against Scotland at Murrayfield on Sunday (3pm).
Scotland are desperate to beat us at this stage. We've beaten them ten times in a row.
Tom Jordan starts and centre as one of three changes for Scotland for Sunday's visit of Ireland to Murrayfied.