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Despite the Limerick outfit claiming a victory the last time these two teams met in the Rainbow Cup, the Dubliners have generally held the upper hand over the last few years.
Leinster outscored Munster by four tries to one to earn a 34-19 bonus-point win at Thomond Park which extends their lead at the top of the United Rugby Championship to 10 points.
Munster and Leinster have called upon 11 of Ireland's Six Nations squad to start in their United Rugby Championship clash tomorrow at Thomond Park (7pm, live on RTÉ).
Jason Jenkins looks set to make his return for Munster on Friday, having resumed full training this week.
Iain Henderson, Jack Conan and Mack Hansen have all been brought into the Ireland team for the final round of the Guinness Six Nations against Scotland this Saturday.
Ireland coach Andy Farrell has named the following team to play Scotland in their Six Nations Championship fixture in Dublin on Saturday.
Munster out-half Jake Flannery has agreed a move to Ulster for next season.
James Ryan has been ruled out of Ireland's final Guinness Six Nations match against Scotland.