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Ireland forwards Caelan Doris and Rónan Kelleher are injury doubts ahead of Saturday's Six Nations clash with Wales, while Iain Henderson and Cormac Izuchukwu are definitely out.
Ireland second-row Iain Henderson has been ruled out of their Guinness Six Nations trip to Wales and skipper Caelan Doris is a major doubt for the Cardiff clash.
The addition of an Ireland 'A' fixture has added a little extra spice to this weekend’s URC action with a number of fringe players looking to impress.
Denied a player of the match award by Lawrence Dallaglio despite running in a hat-trick of tries, Cormac Izuchukwu took it all in his stride.
Munster will go head-to-head with club legend and former out-half Ronan O'Gara as they will face La Rochelle in the last 16 of the Investec Champions Cup.
Cormac Izuchukwu plundered a hat-trick of tries as Ulster ended their Investec Champions Cup pool stage campaign with a 52-24 hammering of Exeter at Kingspan Stadium.
Ireland international Rob Herring returns for Ulster on Friday night, one of five changes to Richie Murphy's side as they look to keep their slim hopes of reaching the Investec Champions Cup knockout stage alive.
Interim Ireland head coach Simon Easterby has named his squad for the Guinness Six Nations with just one uncapped player, Leinster's Jack Boyle, included.