Reigning champions Real Madrid secured their place in the Copa del Rey last 16 with a 3-1 win at fourth-tier Arandina on Saturday. Atletico Madrid progressed with a 3-1 win at third-tier Lugo after Memphis Depay struck twice, while Real Betis were knocked out in a 1-0 defeat by Alaves. Surprise La Liga title challengers Girona beat second division side Elche 2-0. Minnows Arandina fought gamely in the first half but Joselu put Madrid ahead with a penalty early in the second, with Brahim Diaz and Rodrygo Goes expanding Madrid's lead.