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Adam Schefter - Brandon Aiyuk - Source - 49ers leading WR Brandon Aiyuk likely out vs. Giants - ESPN - espn.com - New York - San Francisco - Los Angeles

Source - 49ers leading WR Brandon Aiyuk likely out vs. Giants - ESPN

San Francisco 49ers wide receiver Brandon Aiyuk is not expected to play Thursday night against the New York Giants because of a shoulder injury, a league source told ESPN's Adam Schefter.

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Tyler Fulghum - 49ers-Giants Thursday Night: NFL betting odds, picks, tips - ESPN - espn.com - New York - San Francisco - state Arizona - county Santa Clara

49ers-Giants Thursday Night: NFL betting odds, picks, tips - ESPN

An undermanned New York Giants offense that will be without Saquon Barkley faces the San Francisco 49ers (-10, 44.5) at Levi's Stadium on Thursday night.

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Joe Burrow - Donovan McNabb says slow offense across NFL is result of lack of starters' preseason time - foxnews.com - San Francisco - county Eagle - county Leon - state California - county Park

Donovan McNabb says slow offense across NFL is result of lack of starters' preseason time

Fox News Flash top sports headlines are here. Check out what's clicking on Foxnews.com.

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Cam Akers - Kevin Oconnell - Rams trade running back Cam Akers to Vikings as part of 2026 draft pick swap: reports - foxnews.com - San Francisco - county Eagle - Los Angeles - state Minnesota - state California - county Bay

Rams trade running back Cam Akers to Vikings as part of 2026 draft pick swap: reports

Fox News Flash top sports headlines are here. Check out what's clicking on Foxnews.com.

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Adam Schefter - Brian Daboll - Saquon Barkley - Giants' Saquon Barkley ruled out vs. 49ers due to ankle injury - ESPN - espn.com - county Miami - New York - San Francisco - state Arizona

Giants' Saquon Barkley ruled out vs. 49ers due to ankle injury - ESPN

TEMPE, Ariz. — New York Giants star running back Saquon Barkley has been ruled out for Thursday night's matchup against the San Francisco 49ers because of an ankle injury.

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Sean Macvay - Gary A.Vasquez - Rams' Sean McVay 'not aware' of gambling implications when team kicked meaningless field goal vs 49ers - foxnews.com - Usa - San Francisco - Los Angeles - state California - county Stafford

Rams' Sean McVay 'not aware' of gambling implications when team kicked meaningless field goal vs 49ers

Fox News Flash top sports headlines are here. Check out what's clicking on Foxnews.com.

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Kyle Shanahan - NFL Week 3 Power Rankings 2023: How all 32 teams stack up - ESPN - espn.com - Washington - New York - San Francisco

NFL Week 3 Power Rankings 2023: How all 32 teams stack up - ESPN

Week 2 of the NFL regular season was a rebound week for several teams, most notably the Buffalo Bills, Kansas City Chiefs and New York Giants, while others are still struggling to find their footing (the Cincinnati Bengals).

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Adam Schefter - Brian Daboll - Star - Giants won't yet rule out 'quick healer' Saquon Barkley - ESPN - espn.com - New York - San Francisco - state Arizona - state California

Giants won't yet rule out 'quick healer' Saquon Barkley - ESPN

TEMPE, Ariz. — New York Giants coach Brian Daboll refused to rule out Saquon Barkley despite an ankle injury his star running back suffered in Sunday's 31-28 victory over the Arizona Cardinals.

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