Three-time champion Novak Djokovic will take on third seed Daniil Medvedev in the US Open men's singles final on Monday. As Djokovic again stands on the verge of history at the US Open, he has a score to settle with Medvedev after his loss to the Russian in the 2021 final cost him a calendar Grand Slam. Medvedev defeated Djokovic in straight sets two years ago to prevent the Serbian from becoming the first man to win all four Grand Slams in the same year since Australian great Rod Laver in 1969. Earlier this year, Djokovic fell short of Margaret Court's all-time mark for most Grand Slam singles titles (24) after losing to Carlos Alcaraz in the Wimbledon final.