Karen Khachanov set-up a US Open semi-final duel with Casper Ruud on Tuesday when he battled past "devastated" Nick Kyrgios in a big-hitting five-setter, shattering the Australian crowd-pleaser's dreams of a maiden Grand Slam title. Russian 27th seed Khachanov triumphed 7-5, 4-6, 7-5, 6-7 (3/7), 6-4 over the Wimbledon runner-up to make the last-four at a major for the first time. Earlier Tuesday, Norwegian fifth seed Ruud defeated Italy's Matteo Berrettini 6-1, 6-4, 7-6 (7/4) to make his second Slam semi-final of 2022 having finished runner-up to Rafael Nadal at the French Open.